Thyroid Function in Men Taking Carbamazepine, Oxcarbazepine, or Valproate for Epilepsy
نویسندگان
چکیده
منابع مشابه
Reproductive effects of valproate, carbamazepine, and oxcarbazepine in men with epilepsy.
BACKGROUND Recent observations have indicated that reproductive endocrine disorders are common among women taking valproate (VPA) for epilepsy, but it is not known whether respective abnormalities develop in men taking VPA for epilepsy. Carbamazepine (CBZ) may induce endocrine disorders in men with epilepsy, but the endocrine effects of oxcarbazepine (OXC) are not known. METHODS Reproductive ...
متن کاملphenytoin, carbamazepine or sodium valproate attending an epilepsy clinic
To assess the most efficient means of monitoring thyroid status in an epilepsy clinic, total thyroxine (T4), free thyroxine (FT4) and thyroid stimulating hormone (TSH) were measured in 71 adult patients treated long-term with either phenytoin (DPH), carbamazepine (CBZ) or sodium valproate (VAL). Twenty-seven patients with one or more abnormal thyroid hormone results were further investigated by...
متن کاملThe cognitive effects of oxcarbazepine versus carbamazepine or valproate in newly diagnosed children with partial seizures
OBJECTIVE To investigate the effect of oxcarbazepine against standard antiepileptic drug therapy (carbamazepine and valproate) on cognitive function in children and adolescents (aged 6 to <17 years) with newly diagnosed partial seizures. METHODS A multicentre, open-label, randomised, active-control, three-arm, parallel-group, 6-month study. The primary cognitive variable, the Computerized Vis...
متن کاملThe effective evaluation of thyroid status in patients on phenytoin, carbamazepine or sodium valproate attending an epilepsy clinic.
To assess the most efficient means of monitoring thyroid status in an epilepsy clinic, total thyroxine (T4), free thyroxine stimulating hormone (TSH) were measured in 71 adult patients treated long-term with either phenytoin (DPH), carbamazepine (CBZ) or sodium valproate (VAL). Twenty-seven patients with one or more abnormal thyroid hormone results were further investigated by a thyrotrophin re...
متن کاملThyroid hormones in children with epilepsy during long-term administration of carbamazepine and valproate.
OBJECTIVE This study evaluates the effects of long-term carbamazepine (CBZ) and valproate acid (VPA) therapy on thyroid function in epileptic children. DESIGN A prospective study performed in 32 newly diagnosed pediatric patients, subdivided into two groups: 18 patients treated with CBZ and 14 patients treated with VPA. Thirty-two sex- and age- matched subjects served as controls. METHODS S...
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ژورنال
عنوان ژورنال: Epilepsia
سال: 2001
ISSN: 0013-9580,1528-1167
DOI: 10.1046/j.1528-1157.2001.042007930.x